Conclusions The NDPSS1 and NDPSS2 increased pathologists' scoring burden without improving reproducibility. Pathologist feedback indicated the NDPSS1 and NDPSS2 were time-consuming. Using the Gwet AC 1, 79% of the original NDPSS descriptors had good or excellent agreement.
Mean (standard deviation) differences in agreement estimates using the NDPSS1 and NDPSS2 compared with the single-level original NDPSS were -0.09 (0.17) and -0.17 (0.17), respectively. Greater agreement was achieved using the Gwet AC 1 compared with the Cohen κ across all scoring methodologies. Results Overall, pathologists' uncertainty was low, favoring application of the Gwet AC 1. Agreement was tested using conventional (Cohen κ) and alternative (Gwet agreement coefficient 1 ) agreement statistics and compared with previously published data (original NDPSS). Three and 5 pathologists scored 157 and 79 glomeruli using the NDPSS1 and NDPSS2, respectively. Design The original NDPSS was modified (NDPSS1 and NDPSS2) to evaluate (1) independent scoring of each individual biopsy level, (2) use of continuous measures, (3) groupings of individual descriptors into classes and subclasses prior to scoring, and (4) indication of pathologists' confidence/uncertainty for any given score. Objective To test reproducibility and feasibility of alternative scoring strategies for digital morphologic assessment of glomeruli and explore use of alternative agreement statistics. Our previous study using the descriptor-based Nephrotic Syndrome Study Network Digital Pathology Scoring System (NDPSS) on glomerular images revealed variable reproducibility. Holzman), University of Pennsylvania, Philadelphia the Department of Pathology, Johns Hopkins University, Baltimore, Maryland (Drs Bagnasco and Rosenberg) the Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland (Dr Rosenberg) the Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland (Dr Hewitt) and the Department of Pathology, University of Miami, Miami, Florida (Dr Barisoni).Ĭontext Testing reproducibility is critical for the development of methodologies for morphologic assessment. 1 From Biostatistics, Arbor Research Collaborative for Health, Ann Arbor, Michigan (Dr Zee) the Departments of Pathology (Dr Hodgin), Internal Medicine (Dr Mariani), and Biostatistics (Dr Gillespie), University of Michigan, Ann Arbor Arbor Research Collaborative for Health, Ann Arbor, Michigan (Dr Mariani) the Department of Pathology & Immunology, Washington University, St Louis, Missouri (Dr Gaut) the Departments of Pathology and Laboratory Medicine (Dr Palmer) and Medicine (Dr.NAMEĤ001 W MARKET ST LOUISVILLE, KY 402122540ĩ269 LAMBORNE BLVD APT 1 LOUISVILLE, KY 40272ĩ188 OLD BOWLING GREEN PARK CITY, KY 42160Ģ30 W ESPLANADE AVE LOUISVILLE, KY 402142755Ĥ04 WILLIAMS ST JEFFERSONVILLE, IN 471306355Ĥ000 EMERALD SPRINGS PL LOUISVILLE, KY 40245Ĥ56 S 11TH ST BLDG #26 LOUISVILLE, KY 40203Ģ809 FIELDSTONE DR SE CONYERS, GA 300134924Ħ811 BARFIELD RD LOUISVILLE, KY 402582665Ģ220 GRIFFITHS AVENUE LOUISVILLE, KY 40212ġ0036 WHIPPS MILL ROAD LOUISVILLE, KY 40223Ģ300 W MUHAMMAD ALI BLVD LOUISVILLE, KY 40212ģ013 DUNCAN STREET LOUISVILLE, KY 402121830ġ422 SAN ANDRES ST SANTA BARBARA, CA 93101Ģ702 GLEESON LN APT 2 LOUISVILLE, KY 40299ģ753 WOODGREEN CT APT 3 LOUISVILLE, KY 40215Ħ004 BRISTOL BLUFF CIRCLE LOUISVILLE, KY 40229ġ02 BILLY ROBB ST LOT 7 GREENBRIER, TN 37073ġ0503 WHITEPINE VIEW PLACE LOUISVILLE, KY 40299ĥ132 HUNTERS POINT CIRC LOUISVILLE, KY 40216ģ007 TEAKWOOD CIRCLE LOUISVILLE, KY 40216ħ00 EAST MUHAMMAD ALI BLVD LOUISVILLE, KY 402021643Ĥ00 S 8TH ST APT 407 LOUISVILLE, KY 40203ģ610 GREEN MEADOWS APT A1 LOUISVILLE, KY 40218ġ117 SHELBYVILLE ROAD TAYLORSVILLE, KY 40071Ĥ54 S 11TH STREET BLDG 26 LOUISVILLE, KY 402031849ĥ115 QUAIL HOLLOW RD LOUISVILLE, KY 40213ĩ589 FOUR WINDS DR APT 221 ELK GROVE, CA 95758Ħ73 LINDELL AVE. Learn more about the 2021 Delinquent Child Support List. If you do not believe you owe the amount listed or you believe your name was published in error, we can review and possibly modify your case.Īmounts listed are owed as of March 2021. All information received by this agency is confidential. If your name appears on this list or if you know the location or employer of anyone listed, please contact us.
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